Actuarial Maths & Statistics, Heriot-Watt Univ : http://www.hw.ma.ac.uk/ams/res/girc.html

The Genetics and Insurance Research Centre

Publications: Additional Information


Publication Policy

All the research work of the Genetics and Insurance Research Centre (GIRC) will be in the public domain. Research reports will be placed on this website and submitted to refereed journals for publication. Additional information may be made available on this page.


Research Report 01/1 A Nelson-Aalen Estimate of of the Incidence Rates of Early-Onset Alzheimer's Disease Associated With the Presenilin-1 Gene, by Eng Hock Gui and Angus Macdonald.

This report included graphs of estimated intensities and onset of EOAD, and probabilities of survival free of EOAD, with confidence intervals. The values of these estimates at integer ages are given below. Note the suggestion in the paper, that these should not be used directly in any application but may guide the choice of suitable functions, and their extrapolation beyond about age 45.


For more information, please contact the director of GIRC, Prof Angus Macdonald (+44(0)131-451-3209 or A.S.Macdonald@ma.hw.ac.uk).

Last updated 9 April 2001